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Academic Information

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Lola Llorente Ortega is graduated in Biology by Autonomous University of Madrid and with a MSc in Genetic Manipulation and Molecular Cell Biology (University of Sussex, UK). Due to my interest in Genetics, the last year of the Biology Degree was focused on the specialization in this area and I developed my final degree project at the Institute of Medical and Molecular Genetics (INGEMM), Hospital La Paz. The work was based on the use of molecular techniques such as sequencing and comparative analysis in order to confirm or refute previous clinical diagnoses of patients apparently affected by a a overgrowth syndrome.


My interest related to genetic manipulation led me to take a master's degree in Genetic Manipulation and Molecular Cell Biology at the University of Sussex (Brighton, UK) in 2017. The final master's thesis was developed at the “Genome Damage and Stability Center” and it was based on the study of the correlation between the formation of R-loops and genomic instability.

Since my research interest is related to Molecular Genetics, currently I am developing my 3rd year of doctoral thesis in the Biology and Environmental Toxicology group at National Distance Education University (UNED). The main purpose of my research line is the analysis of the effect of emerging pollutants, in model and non-model species, through molecular and cellular biomarkers.

Academic positions held

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Teaching

Docencia

Research

PROYECTOS DE INVESTIGACIÓN

  • Toxicology Innovative Learning for Europe (ToxLearn4EU). KA220-HED – Cooperation partnerships in higher education. 2022 - 2025. Proyecto 2021-1-FR01-KA220-HED-00003081. Equipo de investigación.  Erasmus + (2021).
  • Re-thinking active learning for distance education Re-thinking active learning for distance education
  • Laboratorios virtuales BIOINNOVA: Aproximación a los cefalópodos mediante una práctica disección onlin 2021 - 2022. Proyectos de Innovación Docente UNED (Madrid, Spain)
  • Evaluation of the biocidal potential of methyl ketones in insects of agricultural relevance: implications and risks derived from their use in integrated pest managements 2020 - 2022. UNED-Santander Young Talent 2020 (Madrid, Spain).

Publications

  • PUBLICATIONS IN MAGAZINES Llorente, L. (2018). Semblanza de los premios Nobel 2018 en Fisiología o Medicina. 100cias UNED.


    Llorente, L. (2018). Taller y laboratorio: Rosalind Franklin: la madre del ADN. Jugando con Ciencia. 100cias UNED.

     

    Más información sobre artículos publicados:

    RESEARCHEGATE

    ORCID

    LINKEDIN

     
  • PUBLICATIONS AT CONFERENCES  Llorente L., Aquilino M., Beaugeard L., Herrero Ó., Annick M., Siaussat D., Lecureuil L., Planelló R. Toxic effects of methyl ketones in the insect model species Nasonia vitripennis: potential alternatives to synthetic insecticides?. Poster. 56th Congress of the European Societies of Toxicology. Toxicology of the next generation (EUROTOX 2021). Virtual congress. 26 September – 1 October 2021.
     
    ▪ Aquilino M., Planelló R., Llorente L., Siaussat D., Herrero Ó. Assessement of the toxic effects of 2-dodecanone in the insect model species Drosophila melanogaster. Poster. 56th Congress of the European Societies of Toxicology. Toxicology of the next generation (EUROTOX 2021). Virtual congress. 26 September – 1 October 2021.   

    ▪ Llorente L., Herrero Ó., Aquilino M., Planelló R. Prodiamesa olivacea: new immune and stress biomarker genes in a potential sentinel organism for ecotoxicity studies in natural scenarios. Poster. European Environmental Mutagenesis & Genomic Society annual meeting (EEMGS 2021). Virtual congress. 24 June 2021.

    ▪ Aquilino M., Llorente L., Jiménez-Florido P., Herrero Ó., Buckley D., Bella J.L., Planelló R. Evaluation of the physiological response of Chorthippus parallelus (Orthoptera) to Wolbachia infection: characterization of new molecular biomarkers. Poster. European Environmental Mutagenesis & Genomic Society annual meeting (EEMGS 2021). Virtual congress. 24 June 2021.

    ▪ Llorente L., Herrero Ó., Aquilino M., Planelló R. Prodiamesa olivacea, a potential sentinel organism for ecotoxicity studies in natural scenarios. Oral communication. XXV Reunión Científica de la Sociedad Española de Mutagénesis Ambiental (SEMA 2021). Virtual congress. 22 June 2021.

    ▪ Aquilino M., Planelló R., Llorente L., Siaussat D., Herrero O. Toxic effects of the methyl ketone 2-dodecanone in Drosophila melanogaster. Oral communication. XXV Reunión Científica de la Sociedad Española de Mutagénesis Ambiental (SEMA 2021). Virtual congress. 22 June 2021.

    ▪ Llorente L., Aquilino M., Beaugeard L., Herrero Ó., Annick M., Siaussat D., Lecureuil L., Planelló R. Poster. Toxic effects of the plan secondary metabolite 2-dodecanone in the insect model species Nasonia vitripennis. XLII Congress of the Spanish Genetics Society (SEG 2021). Virtual congress. 14 – 18 June 2021.

    ▪ Aquilino M., Llorente L., Jiménez-Florido P., Herrero Ó., Buckley D., Bella J.L., Planelló R. Poster. Differential gene expression in Chorthippus parallelus (Orthoptera: Acrididae) related to Wolbachia infection. XLII Congress of the Spanish Genetics Society (SEG 2021). Virtual congress. 14 – 18 June 2021.

    ▪ Planelló R., Herrero Ó, Aquilino M., Llorente L. Oral Communication. Evaluation of the biocial potential of plant secondary metabolites in insects. III Conference on Environmental Toxicology and Ecotoxicology (ToxEcotox 2021). Virtual. 26 May 2021.

    ▪ Narváez I., Aquilino M., Escaso F., Herrero Ó., Llorente L., Novo M., Ortega F., Pérez-Martín J.M., Planelló R., Oral communication. BIOINNOVA en tiempos de pandemia: un laboratorio de Biología virtual de acceso universal. XI Conference on Research in Teaching Innovation of UNED. Advances in hybrid and online teaching for post-pandemic education. Online. 11-13 May 2021.

    ▪ Planelló R., Herrero Ó., Llorente L. Oral Communication. Molecular biomarkers for the evaluation of toxic effects in model and non-model invertebrates. II Conference on Environmental Toxicology and Ecotoxicology (ToxEcotox 2019). Madrid. 31 January 2019.

    ▪ Llorente L., Herrero O, Planelló R. Oral communication. Prodiamesa olivacea, a novel non-model organism for ecotoxicity studies in natural scenarios. 4th International Congress on Occupational & Environmental Toxicology (ICOETOX 2018). Matosinhos - Porto (Portugal). 24-26 October 2018.

    ▪ Llorente L., Herrero O., González-Doncel M., Sánchez-Argüello P., Planelló R. Poster. Transcriptional alterations of genetic markers in medaka (Oryzias latipes) exposed to bisphenol S. 4th International Congress on Occupational & Environmental Toxicology (ICOETOX 2018). Matosinhos - Porto (Portugal). 24-26 October 2018.

    ▪ Arambourou H, Herrero O, Llorente L, Moreno I, Delorme N, Méndez-Fernández L, Fuertes I, Barata C, Planelló R. Poster. Effects of field-collected sediments exposure on the health status of Chironomus riparius. 4th International Congress on Occupational & Environmental Toxicology (ICOETOX 2018). Matosinhos - Porto (Portugal). 24-26 October 2018.

    ▪ Llorente L, Herrero O, Planelló R, Beltrán EM, Fernández C, Sánchez-Argüello P. Poster. Life-cycle and genomic effects in Chironomus riparius larvae exposed to reclaimed water and its fortifications. 11º Congreso Ibérico y 8º Iberoamericano de Contaminación y Toxicología Ambiental (CICTA). Madrid (Spain). 11-13 July 2018.

    ▪ Planelló R, Llorente L, Blanco L, de la Peña E, Herrero Ó.   Oral communication. Toxic effects of methyl ketones in the insect model species Chironomus riparius: potential alternatives to synthetic insecticides? 11º Congreso Ibérico y 8º Iberoamericano de Contaminación y Toxicología Ambiental (CICTA).  Madrid (Spain). 11-13 July 2018.

    ▪ Planelló R, Herrero Ó, Llorente L, Gómez-Sande P, Cobo F, Servia MJ.  Poster. Differential responses to polluted environments in Chironomus riparius larvae: a case study in a natural scenario. 11º Congreso Ibérico y 8º Iberoamericano de Contaminación y Toxicología Ambiental (CICTA). Madrid (Spain). 11-13 July 2018.

    ▪ Pla C, Herrero Ó, Llorente L, Blanco L, de la Peña E, Planelló R. Oral communication. Toxic effects of 2-dodecanone in the insect model species Chironomus riparius: potential alternatives of secondary metabolites to synthetic insecticides. XXIV Reunión Científica de la Sociedad Española de Mutagénesis Ambiental (SEMA 2018). Madrid (Spain). 20-22 June 2018.

    ▪ Llorente L, Herrero Ó, Aquilino M, Planelló R. Oral communication. Prodiamesa olivacea as a novel non-model organism for ecotoxicity studies in natural scenarios. XXIV Reunión Científica de la Sociedad Española de Mutagénesis Ambiental (SEMA 2018). Madrid (Spain). 20-22 June 2018.

    ▪ Servia MJ, Herrero Ó, Llorente L, Gómez-Sande P, Cobo F, Planelló R. Oral communication. Complex responses in complex scenarios: the use of biomarkers in Chironomus riparius larvae in a polluted river. XXIV Reunión Científica de la Sociedad Española de Mutagénesis Ambiental (SEMA 2018). Madrid (Spain). 20-22 June 2018.
    ▪ Herrero Ó, Planelló R, Llorente L, Beltrán EM, Fernández C, Sánchez-Argüello P. Oral communication. Transcriptional changes in hormone-related genes and developmental/reproductive effects in Chironomus riparius larvae exposed to reclaimed water. Workshop Hormones and Behaviours in arthropods. Tours (France) 5-6 June 2018.

    ▪ Planelló R, Llorente L, Pla C, Bella JL, Arroyo F, de la Peña E, Blanco L, Ferrero V, Herrero Ó. Keynote. Evaluation of endocrine response, through genetic biomarkers, in model and non-model insects. Workshop Hormones and Behaviours in arthropods. Tours (France) 5-6 June 2018.
Otros

Other activities

Permanent education

▪ Webinar for universities: Biosafety principles. Prevention and action in the event of a biological accident. FREMAP (Madrid, April 2021).

▪ Webinar for universities: Biological agents. FREMAP (Madrid, April 2021).

▪ Gamification in aLF. Instituto Universitario de Educación a Distancia (IUED-UNED, Madrid, November-December 2020).

▪ QuantStudio Real Time PCR SmartStart Orientation. ThermoFisher Scientific – applied biosystems (Madrid, October 2020).
▪ Advanced course in statistics in R. Instituto Universitario de Educación a Distancia (IUED-UNED, Madrid, May 2019).

▪ Preprocessing data in R. Instituto Universitario de Educación a Distancia (IUED-UNED, Madrid, May 2019).

▪ Introduction to statistics in R. Instituto Universitario de Educación a Distancia (IUED-UNED, Madrid, May 2019).

▪ RNA-sequence Analysis. European Bioinformatics Institute (EMBL-EBI, Cambridge, April 2019).

▪ SPSS data analysis advance level. Instituto Universitario de Educación a Distancia (IUED-UNED, Madrid, January 2019).

▪ SPSS data analysis beginner level. Instituto Universitario de Educación a Distancia (IUED-UNED, Madrid, January 2019).

 

 Experience in educational, scientific and technological management and administration

Representante Personal Docente e Investigador, SIGC - Junta de Facultad (Facultad de Ciencias, UNED).

 Others

ABROAD INTERNSHIPS

(November 2021). Research Institute of Insect Biology (UMR 726 CNRS-University of Tours)

Study of the impact of the potential endocrine disruptor bisphenol-S on development and molecular pathways of Nasonia vitripennis under the supervision of Dr. Charlotte Lecureuil.


(October 2021). Insect-pathogen interaction (In.Path.In). Universitat de Vàlencia. (Valencia, Spain).

I studied the modes of toxic action of different methyl ketones and xenobiotics in the insect pest model Spodoptera exigua under the supervision of Dr. Salvador Herrero. In addition, I carried out the bioassay optimization as well as the integrative analysis of classical toxicological parameters.

 

(February - July 2021). Institute of Ecology and Environmental Sciences of Paris (iEES). Marie Curie and Pierre University (UPCM). Sorbonne University (Paris).

Internship co-founded by grants:
• UNED-Santander 2020/2021 International Mobility for EIDUNED doctorates  
• UNED ERASMUS + Doctorates International Mobility.
Six months research internship in the laboratory of Dr. David Siaussat. I carried out the use of ecotoxicology integrative methodology to determine the mechanism of action of different methyl ketones in the insect pest model Spodoptera littoralis. In addition, I evaluated their potential activity as natural biocides in integrated pest management.


(December 2019). Research Institute of Insect Biology (UMR 726 CNRS-University of Tours).

Optimization of molecular analyses, setting up Comet assay and experiments of Nasonia vitripennis under the supervision of Dr. Charlotte Lecureuil.


(October 2019). Ecotoxicology and Animal Physiology Laboratory, Biology Department University of Aveiro (Aveiro, Portugal).

Development of oxidative stress assays in the framework of my thesis work and scientific collaboration between Dr. Sofia Guilherme (UAveiro, Portugal) and Dr. Rosario Planelló and Dr. Óscar Herrero (UNED, Spain).


(September 2018). National Research Institute of Science and Technology for Environment and Agriculture, IRSTEA (Lyon, France).
 
Set up of an experimental assay in collaboration with Dr. Hélène Arambourou to acquire knowledge and skills to perform similar experimental procedures in ecotoxicology studies to enrich research lines in course.